Senior Associate Scientist - Therapeutic Cargo Design (In-Vitro)

Location: Tarrytown
Posted on: June 23, 2025

Job Description:

We are seeking a creative and highly motivated Senior Associate Scientist to join our Editing Technologies and Therapeutic Cargo Group within Regeneron Genetic Medicines. You will work both cross-functionally with colleagues as well as independently to develop and implement assays to support the discovery, characterization, and development of next-generation gene therapy technologies to target multiple organ systems, especially the central nervous system (CNS). As a Senior Associate Scientist, a typical day may include the following: Performing cell-based assays using transfection and viral vector transduction techniques in BSL2 mammalian cell culture and analyzing transfection efficiency using flow cytometry. Performing RNA and DNA isolation and purification from cell culture and tissue samples Performing molecular biology experiments using qPCR, dPCR, and ddPCR Developing and implementing ELISA and Western blot-based protein expression analysis assays Producing, purifying, quantifying, and characterizing AAV vectors Analyzing and presenting data (familiarity with Graphpad Prism or other statistical/graphical software) Collaborating with therapeutic-focused groups to characterize and optimizing construct designs based on functional activity in various in vitro and in vivo models Participating in team meetings and preparation of presentations for departmental meetings Maintaining accurate documentation of experimental procedures, data, and analysis, including meticulous sample tracking and data management This role may be for you if you: Enjoy working in an innovation driven, highly collaborative, and fast paced environment Have an affinity for technology development-focused projects Are skilled at designing well-controlled experiments that can provide reliable results Can effectively balance multiple projects independently and across groups Possess strong organizational and time-management skills In order to be considered for this opportunity, you must have at least a BS/MS in biology, molecular biology, genome sciences, biochemistry, or a related field with 3 years of relevant experience in an academic or industry laboratory in a relevant field. We need someone with a fundamental understanding of molecular and cellular biology Experience with basic molecular biology techniques such as cell culture, western blot, PCR, cloning, etc. is required. Experience with flow cytometry and knowledge regarding adeno-associated virus (AAV) vector-based gene therapy methods and technologies is a distinct advantage. Familiarity with in vivo experimentation and basic mouse husbandry is a plus. Must be highly organized, enthusiastic, and able to manage multiple projects. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $79,100.00 - $129,100.00

Keywords: , East Hartford , Senior Associate Scientist - Therapeutic Cargo Design (In-Vitro), Science, Research & Development , Tarrytown, Connecticut